2020 Suddath Symposium
Redox Homeostasis and Signaling in Human Health and Disease
Parker H. Petit Institute for Bioengineering and Bioscience
January 9-10, 2020
DAY 1 - THURSDAY, JANUARY 9, 2020
Suddath Seminar Room 1128
11:00 a.m. 2020 Suddath Award Winner Presentation - "DNA Mechanotechnology for Sensing and Generating Piconewton-scale Forces" - Aaron Blanchard, Doctoral Candidate; Khalid Salaita, Ph.D., Advisor
1:00 p.m. Welcome address – Melissa Kemp, Ph.D. and Amit Reddi, Ph.D.
Session I – Mitrochondrial Control over Cellular Redox Homeostasis
Session Chair – Amit Reddi, Ph.D. – Georgia Tech
1:10 p.m. Keynote Presentation - "Systems Approaches to Mitochondrial Biology and Disease"
Vamsi Mootha, M.D. – Harvard Medical School / Massachusetts General Hospital
2:00 p.m. "Regulation of Redox Homeostasis through Mitochondrial Domain Remodeling"
Young Jang, Ph.D. – Georgia Tech
2:30 p.m. "Mitochdrondrial Metabolic Capacity Determines Maximal Myocardial Mechanical Power Output in Health
Daniel Beard, Ph.D. – University of Michigan Medical School
3:00 p.m. Break
Session II – Redox Systems Biology
Session Chair – Melissa Kemp, Ph.D. – Georgia Tech / Emory University
3:30 p.m. "Patient-specific Computational Modeling of Redox Metabolic Systems"
Melissa Kemp, Ph.D. – Georgia Tech / Emory University
4:00 p.m. "Antagonistic Pleiotropy in Redox Signaling and Control"
Dean Jones, Ph.D. – Emory University School of Medicine
4:30 p.m. "Cysteine-mediated Redox Signaling: Chemical Tools for Biological Discovery"
Kate Carroll, Ph.D. – Scripps Research Institute
5:00 p.m. Presentation of 2020 Suddath Award Winner
5:10 p.m. Poster session and reception – Petit Biotech Atrium
DAY 2 - FRIDAY, JANUARY 10, 2020
Suddath Seminar Room 1128
8:15 a.m. Breakfast
Session III – ROS Generation and Sensing
Session Chair – Susan Smith, Ph.D. – Kennesaw State University
9:00 a.m. "Prokaryotic Noxes: Bigger Hammers for Structure-function Basics"
Susan Smith, Ph.D. – Kennesaw State University
9:30 a.m. “Redox Signaling through NOX and Mitochondria in Angiogenesis and Ischemic Disease”
Masuko Ushio-Fukai, Ph.D. – Medical College of Augusta University
10:00 a.m. "Chemical Tools for Investigating Reactive Sulfur Species"
Mike Pluth, Ph.D. – University of Oregon
10:30 a.m. "The Dual Roles of Cu/Zn Superoxide Dismutase (SOD1) in Defense Against Oxidative Stress and
Amit Reddi, Ph.D. – Georgia Tech
11:00 a.m. Break
11:15 a.m. Panel Discussion – "The Future of Redox Biology"
- Dan Beard, Ph.D. – University of Michigan Medical School
- Christina Furdui, Ph.D. – Wake Forest School of Medicine
- Dean Jones, Ph.D. – Emory University School of Medicine
- Susan Smith, Ph.D. – Kennesaw State University
12:00 p.m. Lunch
Session IV – Redox Pathophysiology and Pathology
Session Chair – Andrew Niesh, M.D. – Emory University School of Medicine
1:00 p.m. "Tissue Redox Signaling Induced by the Microbiota"
Andrew Neish, M.D. – Emory University School of Medicine
1:30 p.m. "Opportunities for Cancer Diagnosis and Treatment through Integrated Redox Biology"
Cristina Furdui, Ph.D. – Wake Forest University School of Medicine
2:00 p.m. “Computational Modeling of Bistability in H2O2 Signaling and the Redox Circadian Rhythm of
Qiang Zhang, Ph.D. – Emory University
2:30 p.m. "Redox-dependent Regulation of the Endothelial N-Glycome: Implications for Inflammatory Cell Trafficking"
Rakesh Patel, Ph.D. – University of Alabama at Birmingham
3:00 p.m. Closing remarks
3:05 p.m. Adjourn