Cardiovascular diseases are the leading causes of death and disability worldwide. We are dedicated to developing new therapies to help cardiac patients by identifying, testing, and moving new therapies towards clinical use. We study stem cell therapies to prevent heart damage and promote repair. We use biomaterials to increase cell retention, increase efficacy, and target activity.
Dr. Taylor’s laboratory is focused on obtaining a better understanding of the role of vascular inflammation in the pathogenesis of vascular disease. His work employs novel animal models of human vascular disease to study the role of various mechanical and humoral factors in the development of hypertension and atherosclerosis. He has a particular interest in the renin angiotensin system, advanced glycation endproducts, biomechanical forces and oxidative stress. A significant effort is also underway to examine the interaction between vascular inflammation and bone marrow-derived endothelial progenitor cells. Dr. Taylor’s research program involves strong collaborative efforts with other members of the Department of Biomedical Engineering with a focus on applying enabling nanotechnology and imaging approaches to the general area of atherosclerosis.
The Yoon Lab has been working on stem cell research in various cardiovascular diseases. Our major research interest is to use stem cell technology to treat various cardiovascular diseases, and we have been developing and using different bone marrow-derived stem sell or progenitor cells for cardiovascular repair.