NEW TWO-SPEAKER FORMAT for 2019-2020!
Costas Arvanitis, Ph.D.
George W. Woodruff School of Mechanical Engineering
AT 8:30 AM:
"Converting Mechanistic Understanding of Ultrasound-mediated Mass Transport to Effective Treatments against Brain Diseases"
Costas Arvanitis’ research is focused on biomedical ultrasound and image guided therapy. His work focuses on understanding the biological effects of ultrasound and of acoustically induced microbubble oscillations (acoustic cavitation) and using them to study complex biological systems, such as the neurovascular network and the tumor microenvironment, with the goal of developing novel therapies for the treatment of cancer and central nervous system diseases and disorders.The current research efforts of the lab are focused on the study of the interactions of ultrasound with single and multiple cells and cell types, ultrasound mediated transport of molecules and pharmaceuticals across cellular and vascular barriers, and microbubble dynamics in vessels and tissues.
To facilitate our research, we engineer and integrate multi-modality and multi-scale systems with numerical models and in vivo and in vitro experimentation. We envision that such systems and approaches will allow us to study and understand biological systems in a completely different way, resulting in new concepts, tools and methods to treat cancer and central nervous system diseases and disorders.
Costas Arvanitis, Ph.D., joined Georgia Institute of Technology as a joint Assistant Professor at the George W. Woodruff School of Mechanical Engineering and the Wallace H. Coulter Department of Biomedical Engineering in August 2016. Before joining Georgia Institute of Technology he was Instructor (Research Faculty) at Harvard Medical Scholl and Brigham and Women’s Hospital. Arvanitis has also worked as a research fellow in the Biomedical Ultrasonics, Biotherapy and Biopharmaceuticals Laboratory at the Institute of Biomedical Engineering at the University of Oxford.
AT 9:00 AM:
Thomas Orlando, Ph.D.
School of Chemistry and Biochemistry
"Low-energy Electron Interactions with Complex Biomolecules and Carcinogenesis"
Professor Orlando directs the Electron- and Photon-Induced Chemistry on Surfaces Lab (EPICS). EPICS is primarily a surface chemistry and physics group that focuses on the use of high-powered pulsed lasers, low-energy electron scattering, micro-plasmas, mass spectrometry, and ultrahigh vacuum surface science techniques. The unifying theme within the group is to understand the important role electronic excitations of surfaces and interfaces play in chemical transformations, which can occur in radiation environments within the interstellar media, plasmas, or planetary magnetospheres. Understanding nonequilibrium processing of surfaces and materials within and beyond our solar system is a specific area of focus, particularly the role of electrons, protons, and extreme ultraviolet radiation in transforming surfaces of planets, their satellites (moons), asteroids, and comets. In addition, there are major efforts to examine the atomic and chemical composition of meteorite and lunar samples that may hold clues to the details of planet formation and possibly the chemical origin of life. These fundamental efforts are connected to many space missions including the Galileo, Cassini, MESSENGER, Deep Impact, and LADEE. Efforts are also underway that examine the chemical processes that occur in star-forming regions, within the solar nebulae, and on grains within interstellar regions. This research group is also affiliated with the Jet Propulsion Laboratory NAI on "Titan as a Pre-biotic Chemical System" and the John Hopkins University Applied Physics Laboratory Lunar Science and SERVI Institutes.