Biomolecular engineering, especially biocatalysis, biotransformations, and biocatalyst stability
Yeast molecular genetics: genetic control of protein folding and aggregation; yeast models for amyloid disorders; prions; chaperones and stress response; protein based epigenetic inheritance
My research area is biomechanics and mechanobiology, with focus on:
- Glaucoma, including studies of aqueous humour drainage and optic nerve head biomechanics.
- Mechanobiology of Osteoarthritis.
- Flow in the cardiovascular system; relationship between
Cell-based Therapies, Biomaterials, Biomechanics, Micro-CT Imaging
Intercalation-mediated Nucleic Acid Assembly, The Molecular Midwife & the Origin of Life, Nucleic Acid-Cation Interactions, Understanding DNA & RNA Condensation
Computational Biochemical Network Modeling, Role of Oxidative Stress in Immunology and Cancer, Signal Transduction, Proteomic Technologies
The molecular details of how cells survive by recognizing and responding to intracellular signals.
Design, synthesis, and application of complex colloidal materials and assemblies. Applications of polymeric materials to biotechnology.
Stem cell engineering, regenerative biomaterials, cell and tissue engineering, stem cell bioprocessing, stem cell delivery
Using Genomics to Design Personalize Cancer Therapies, The Role Of Non-encoding RNAs in Cancer Cancer Stem Cell Therapy, The Application of Nanotechnology to Cancer Diagnostics and Therapy
Sphingolipid Metabolism & Cell Regulation, Lipidomics & Systems Biology, Tissue Imaging Mass Spectrometry, Macrophage Biology, Lipid Signaling in Disease, especially Cancer