Mitral Valve Mechanics
IBB Faculty
I am interested in looking at human and non-human primate apoptotic differences with regard to cognition and disease.
I am interested in modeling human postural control using simplified representations of the musculoskeletal system. Specifically I am investigating how changes in configuration, such as stance width, affect the stability of human standing.
PhD Candidate at the Georgia Institute of Technology
joel.boerckel@gatech.edu
My primary research interests focus on bone tissue engineering and the effects of mechanical forces during healing. I am interested in mechanical adaptation
regenerative medicine, cell and tissue engineering, biomaterials, fibrotic pathologies, mechanotransduction, integrin/ECM interactions
Microfluidics, image analysis, neurodegeneration, neuronal development
Fibronectin biophysics, fibronectin folding/unfolding, phage display screening.
Cell signaling to steroid hormone, bone tissue engineering
Fluid Mechanics of the right heart, Pulmonary Arterial Hypertension
Fibrin based biomaterials for stem cell homing and recruitment to injured tissues.
Synthetic hydrogels that incorporate cell adhesive and enzymatically-degradable peptides and serve as 3D extracellular matrix analogues for the study of epithelial tissue assembly and maintenance. For instance, when embedded in enzymatically-degradable synthetic hydrogels with cell adhesive
Cell engineering, cell mechanics, adhesion strengthening, receptor-ligand interactions
*photo courtesy of Virginia Lin
cellular neuroscience, synaptic plasticity, neural networks
Cartilage tissue engineering using silk fibroin-derived scaffolds and different cell sources
Cartilage Tissue Engineering, Bioreactor Systems, Microfluidics
My interest include many various types of anti-cancer research, including gold nanoparticle work and small molecule inhibitors. I primarily design, synthesize, characterize and test various novel drugs.
Stem cell engineering for immunotherapies
Researching applying models of cortical computational function to engineering problems such as image recognition, auditory feature extraction, and strategy selection. This is to evaluate the suitability of each cortical simulation to each class of problems, to compare the ability of each to
Biomechanics, Gastrulation, EMT, Developmental Biology, Time lapse microscopy
My research at Georgia Tech has involved examining osteoblast response to titanium surfaces and craniofacial development. I primarily use a mouse model to study craniosynostosis, the abnormal fusion of the skull early in development. My research consists of using micro-CT and advanced image
Denderitic cell response to biomaterials. Dendritic cell response to glycans and glycoproteins. High throughput screening technologies.
I joined the Sambanis Lab in October 2010 and I am pursuing research in the area of stem cell biomanufacturing. I am specifically interested in the encapsulation of mesenchymal stem cells in hydrogels, the controlled amplification and differentiation of these stem cells to specific cell
Lipid uptake and transport by the lymphatics. Quantification via image processing.
Quantification of lymphatic function in lipid uptake and transport using in-vivo imaging.
My research focuses on the engineering of stem cells for regenerative medicine and tissue engineering. More specifically, I focus on the use of biomaterials to promote embryonic stem cell differentiation. I am also interested in the development of stem cells into clinical therapies that can be
For the therapeutic promise of embryonic stem cells (ESCs) to be fully realized, scalable approaches to efficiently direct differentiation must be developed. Directed differentiation methods often rely on the addition of morphogens to monolayer cultures of ESCs, which permits homogeneous
Lymphatic biomechanics, automation and control, dynamic modeling, aerodynamics
In vivo and in vitro characterization of dynamic biomaterials; micro/nano fabrication; mechanotransduction; directing stem cell fate
Orthopaedic and craniofacial tissue engineering and regenerative medicine Adult stem cell biology Chondrogenesis Stem cell-based therapies
stem cell engineering, tendon and ligament tissue engineering
Origins and evolution of the ribosome, RNA-cation interactions, RNA secondary and tertiary structure.
Bone/muscle composite injury model, tissue engineering, mesenchymal stem cell delivery, growth factor delivery
I am working on analysis and interpretation of data from cancer patients. Specializations include microarray and next generation RNASeq data analysis.
Therapeutic Device Design for Treatment of Brain Tumors
Self-Organizing Principles in Neurogenesis
Roles of Glial Cells in the CNS
Adaptive Neural Interfaces
Bio-locomotion
Bio-inspired Design
Dynamic Modeling and Simulation
BioMEMS
Micro/Nano-robotics
Understanding the biodistribution of superparamagnetic iron oxide nanoparticles (SPIOs) for tumor imaging and SPIO-based drug delivery to solid tumors
Medical image processing and computer vision
High-throughput RNA-Seq data analysis, splice-variant detection and analysis, gene expression, cancer biology.
MEMS micro-fluidics computational fluid mechanics micro-manufacturing and micro-machining drug delivery and examination of small things at high shear rates
Multivalent protein kinetics, antigen-antibody particle targeting, thermally robust biosensors
Role of biomaterial properties in peri-implant angiogenesis
Cancer Biology, Nanoparticles for Cancer Drug Delivery and Imaging
Particular interest in C2C12 myoblast differentiation in hydrogels to engineer force actuators functioning as muscle strips.
Use of PEG Hydrogels for the dual delivery of Growth Factors to improve Cardiac regeneration post-Myocardiial Infarction.
Extraction of interstitial fluids using microneedles
Computational analysis of systemic miRNA mediated regulation in ovarian cancer.
Embryonic stem cells (ESCs) represent a promising cell source for tissue engineering and regenerative medicine applications, such as the use of ESC-derived osteoprogenitor cells to repair bone defects. My research examines the osteogenic differentiation and matrix mineralization of embryonic
Atomic Force Microscopy, Contact Acoustic Nonlinearity, Wave Propagation Through Solids, MEMS, Fabrication, Mechanical Design
Broadly speaking, my research interests lies in understanding gene expression and regulation in bacteria. Currently, I am studying how the concerted action of small regulatory sRNAs and the RNA chaperon protein Hfq modulates stress response and virulent gene expression in bacteria. The goal of
Cell Signaling Networks, Optimization, Complex Networks
Vascular biomechanics, growth and remodeling, residual strains, soft tissue constitutive modeling, organ culture, materials testing, cardiovascular physiology, pathology, and interventional therapeutics.
Near-Infrared Imaging, Microneedle Drug Delivery, Lymphatic Filariasis
I am interested in systems biology and its applications for modeling stem cell interactions. I am also interested int stem cells and their potential for use in regenerative medicine.
My research involves developing a novel biomaterial for drug and protein delivery to the osteoarthritic joint. To that end, I collaborate with Dr. Niren Murthy to synthesize an amphiphilic copolymer that forms sub-micron scale particles.
These particles incorporate an interesting new
Design and synthesis of fluorescent mRNA probes for stem cell isolation
Imaging of fluorescent mRNA probes in vitro to validate gene correction
Stem cell bioprocessing; stem cell paracrine actions; microfluidic analysis of stem cell phenotype
low power bioinstrumentation, neuromodulation, assistive technology, wearable and wireless system
Novel enzymes characterization for pure enantiomer compound synthesis. Thesis focus on asymmetric bioreduction of C=C with enoate reductases from the Old Yellow Enzyme family, a flavin proteins that have shown to have broad substrate spectrum and excellent chemo-, and stereoselectivity.
The development of microencapsulation techniques of pancreatic substitutes for the treatment of insulin-dependent diabetes.
